Distinct Regions of Cu(I)·ACE1 Contact Two Spatially Resolved DNA Major Groove Sites
نویسندگان
چکیده
منابع مشابه
A dimer of AraC protein contacts three adjacent major groove regions of the araI DNA site.
Contact sites of AraC protein to the regulatory site araI of the Escherichia coli araBAD operon have been determined by the chemical-interference technique. DNA fragments were chemically modified an average of once per molecule, and fragments that no longer bound AraC were separated by gel electrophoresis from the DNA fragments still able to bind the protein. The contact sites were then determi...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1995
ISSN: 0021-9258
DOI: 10.1074/jbc.270.17.10171